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Our new Apparent+ tissue clearing approach is the one process that delipidates samples with no alter in morphology and with minimum effect on structural integrity.

Megatome is often a vibrating microtome meant to section a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform floor profile, and negligible tissue damage and information loss.

Antibodies might consider weeks to diffuse via only a few millimeters of tissue, having a steep labeling gradient from surface to core.

Operating the CLI directly from a Gradle job is not currently supported. A distribution needs to be established by using gradlew :j2d-cli:distZip to produce a zip file that contains anything necessary to run.

SE utilizes a rotational electric field to disperse really electromobile molecules (for instance antibodies or surfactant micelles) in the course of a porous sample with no harmful electrically charged structures throughout the tissue. This permits 2-4 working day clearing of intact organs,

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Megatome is actually a novel microtome that allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue damage and data loss.

eFLASH is usually a speedy tissue labeling technique that enables for uniform entire-organ staining in twenty rounds of labeling.

The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition speed in the course of intact tissue volumes, whilst its modular structure permits you to enhance and personalize unique elements.

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Leverage the Apparent+ tissue clearing technique, in addition to eFLASH and patented stochastic electrotransport systems, to fast clear and label entire organs. Essential highlights and capabilities involve:

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